Acrylamide-d5 (6CI)

1. 1.1 IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING Product identifiers Product name Product Number Brand Index-No. CAS-No. : : : : : Acrylamide-d5 661635 616-003-00-0 108152-65-4 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratory chemicals, Manufacture of substances 2. 2.1 2.2 HAZARDS IDENTIFICATION Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP] Carcinogenicity (Category 1B) Germ cell mutagenicity (Category 1B) Reproductive toxicity (Category 2) Acute toxicity, Oral (Category 3) Specific target organ toxicity - repeated exposure (Category 1) Acute toxicity, Inhalation (Category 4) Acute toxicity, Dermal (Category 4) Eye irritation (Category 2) Skin irritation (Category 2) Skin sensitization (Category 1) Classification according to EU Directives 67/548/EEC or 1999/45/EC May cause cancer. Possible risk of impaired fertility. May cause heritable genetic damage. Toxic if swallowed. Toxic: danger of serious damage to health by prolonged exposure through inhalation, in contact with skin and if swallowed. Harmful by inhalation and in contact with skin. Irritating to eyes and skin. May cause sensitization by skin contact. Label elements Labelling according Regulation (EC) No 1272/2008 [CLP] Pictogram Signal word - 661635 Danger Hazard statement(s) H301 H312 H315 H317 H319 H332 H340 H350 H361f H372 Precautionary statement(s) P201 P280 P301 + P310 P305 + P351 + P338 P308 + P313 Supplemental Hazard Toxic if swallowed. Harmful in contact with skin. Causes skin irritation. May cause an allergic skin reaction. Causes serious eye irritation. Harmful if inhaled. May cause genetic defects. May cause cancer. Suspected of damaging fertility. Causes damage to organs through prolonged or repeated exposure. Obtain special instructions before use. Wear protective gloves/ protective clothing. IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/ attention. none Statements Restricted to professional users. According to European Directive 67/548/EEC as amended. Hazard symbol(s) R-phrase(s) R45 R46 R20/21 R25 R48/23/24/25 R36/38 R43 R62 S-phrase(s) S53 S45 May cause cancer. May cause heritable genetic damage. Also harmful by inhalation and in contact with skin. Also toxic if swallowed. Also toxic: danger of serious damage to health by prolonged exposure through inhalation, in contact with skin and if swallowed. Irritating to eyes and skin. May cause sensitization by skin contact. Possible risk of impaired fertility. Avoid exposure - obtain special instructions before use. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). Restricted to professional users. 2.3 3. 3.1 Other hazards - none COMPOSITION/INFORMATION ON INGREDIENTS Substances Formula Molecular Weight Component : : C3D5NO 76,11 g/mol Concentration Acrylamide-d5 Included in the Candidate List of Substances of Very High Concern (SVHC) according to Regulation (EC) No. 1907/2006 (REACH) CAS-No. 108152-65-4 - Index-No. - 661635 616-003-00-0 4. 4.1 4.2 4.3 5. 5.1 5.2 5.3 5.4 6. 6.1 6.2 6.3 6.4 7. 7.1 7.2 FIRST AID MEASURES Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Most important symptoms and effects, both acute and delayed Indication of any immediate medical attention and special treatment needed no data available FIREFIGHTING MEASURES Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special hazards arising from the substance or mixture Carbon oxides, nitrogen oxides (NOx) Advice for firefighters Wear self contained breathing apparatus for fire fighting if necessary. Further information no data available ACCIDENTAL RELEASE MEASURES Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal. Reference to other sections For disposal see section 13. HANDLING AND STORAGE Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols.Avoid exposure - obtain special instructions before use. Provide appropriate exhaust ventilation at places where dust is formed. Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store under inert gas. hygroscopic - 661635 7.3 8. 8.1 8.2 9. 9.1 Specific end uses no data available EXPOSURE CONTROLS/PERSONAL PROTECTION Control parameters Components with workplace control parameters Exposure controls Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product. Personal protective equipment Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). PHYSICAL AND CHEMICAL PROPERTIES Information on basic physical and chemical properties a) b) c) d) e) f) g) h) Appearance Odour Odour Threshold pH Melting point/freezing point Initial boiling point and boiling range Flash point Evaporation rate Form: solid no data available no data available no data available Melting point/range: 82 - 86 °C no data available no data available no data available i) Flammability (solid, gas) no data available j) k) l) Upper/lower flammability or explosive limits Vapour pressure Vapour density no data available no data available no data available - 661635 m) Relative density no data available n) o) p) q) r) s) t) Water solubility Partition coefficient: n- octanol/water Autoignition temperature Decomposition temperature Viscosity Explosive properties Oxidizing properties no data available no data available no data available no data available no data available no data available no data available 9.2 10. 10.1 10.2 10.3 10.4 10.5 10.6 11. 11.1 Other safety information no data available STABILITY AND REACTIVITY Reactivity no data available Chemical stability no data available Possibility of hazardous reactions no data available Conditions to avoid no data available Incompatible materials no data available Hazardous decomposition products Other decomposition products - no data available TOXICOLOGICAL INFORMATION Information on toxicological effects Acute toxicity no data available Skin corrosion/irritation no data available Serious eye damage/eye irritation Respiratory or skin sensitization May cause sensitization by inhalation. no data available Germ cell mutagenicity In vivo tests showed mutagenic effects Carcinogenicity Possible human carcinogen IARC: 2A - Group 2A: Probably carcinogenic to humans (Acrylamide-d5) Reproductive toxicity Suspected human reproductive toxicant Specific target organ toxicity - single exposure no data available - 661635 Specific target organ toxicity - repeated exposure no data available Aspiration hazard no data available Potential health effects Inhalation Ingestion Skin Eyes Additional Information RTECS: Not available Harmful if inhaled. Causes respiratory tract irritation. Toxic if swallowed. Harmful if absorbed through skin. Causes skin irritation. Causes serious eye irritation. 12. 12.1 ECOLOGICAL INFORMATION Toxicity Toxicity to fish Toxicity to daphnia and other aquatic invertebrates LC50 - Lepomis macrochirus (Bluegill) - 100 mg/l - 96 h EC50 - Daphnia magna (Water flea) - 160 mg/l - 48 h 12.2 12.3 12.4 12.5 12.6 13. 13.1 14. 14.1 Persistence and degradability no data available Bioaccumulative potential no data available Mobility in soil no data available Results of PBT and vPvB assessment no data available Other adverse effects Harmful to aquatic life. DISPOSAL CONSIDERATIONS Waste treatment methods Product Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Contaminated packaging Dispose of as unused product. TRANSPORT INFORMATION UN number ADR/RID: 2074 14.2 UN proper shipping name ADR/RID: ACRYLAMIDE, SOLID IMDG: ACRYLAMIDE, SOLID IATA: Acrylamide, solid 14.3 Transport hazard class(es) ADR/RID: 6.1 14.4 Packaging group ADR/RID: III 14.5 Environmental hazards ADR/RID: no - 661635 IMDG: 2074 IMDG: 6.1 IMDG: III IMDG Marine pollutant: no IATA: 2074 IATA: 6.1 IATA: III IATA: no 14.6 15. 15.1 15.2 16. Special precautions for user no data available REGULATORY INFORMATION This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. Safety, health and environmental regulations/legislation specific for the substance or mixture no data available Chemical Safety Assessment no data available OTHER INFORMATION Further information The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information this document is based on the resent state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Lookchem shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale.

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